Income Taxes (Details Narrative) - USD ($) $ in Thousands	12 Months Ended
Income Taxes (Details Narrative) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Deferred tax assets net operating loss carry forward	$ 20,633	$ 14,273
Ownership change, description	In general, an ownership change, as defined by Section 382 and 383, results from transactions increasing ownership of certain stockholders or public groups in the stock of the corporation by more than 50 percentage points over a three-year period.
Federal [Member]
Deferred tax assets net operating loss carry forward	$ 54,000
Net operating loss carry forward, expiration	2027
Deferred research tax credit carryforwards	$ 1,200
California [Member]
Deferred tax assets net operating loss carry forward	$ 47,000
Net operating loss carry forward, expiration	2029
Deferred research tax credit carryforwards	$ 300