Transactions with Related Parties (Details Narrative) - USD ($)	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016	Nov. 30, 2014
Rent expenses	$ 47,000	$ 46,000
Royalty payment rate	3.50%
Duke [Member]
Non-refundable license fee	$ 100,000
License Agreement [Member] \| One Year [Member]
Royalty payable	25,000
License Agreement [Member] \| Five Year [Member]
Royalty payable	$ 400,000
Minimum [Member] \| Duke [Member]
Royalty payment rate	2.00%
Minimum [Member] \| License Agreement [Member]
Royalty payable	$ 40,000	$ 500,000
Maximum [Member] \| Duke [Member]
Royalty payment rate	5.00%
Dr. Raymond Schinazi [Member]
Annual lease expense			$ 196,000
Lease expiration	Jun. 30, 2017