Annual report [Section 13 and 15(d), not S-K Item 405]

Cover

v3.26.1
Cover - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2025
Mar. 24, 2026
Jun. 30, 2025
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2025    
Document Fiscal Period Focus FY    
Document Fiscal Year Focus 2025    
Current Fiscal Year End Date --12-31    
Entity File Number 001-38418    
Entity Registrant Name Cocrystal Pharma, Inc.    
Entity Central Index Key 0001412486    
Entity Tax Identification Number 35-2528215    
Entity Incorporation, State or Country Code DE    
Entity Address, Address Line One 19805 North Creek Parkway    
Entity Address, City or Town Bothell    
Entity Address, State or Province WA    
Entity Address, Postal Zip Code 98011    
City Area Code (877)    
Local Phone Number 262-7123    
Title of 12(b) Security Common Stock, par value $0.001 per share    
Trading Symbol COCP    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity Public Float     $ 11.6
Entity Common Stock, Shares Outstanding   13,785,759  
ICFR Auditor Attestation Flag true    
Document Financial Statement Error Correction [Flag] false    
Auditor Firm ID 572    
Auditor Opinion [Text Block] We have audited the accompanying consolidated balance sheets of Cocrystal Pharma, Inc. (the “Company”) and subsidiaries as of December 31, 2025 and 2024, the related consolidated statements of operations, stockholders’ equity, and cash flows for the years then ended, and the related notes (collectively referred to as the “consolidated financial statements”). In our opinion, the consolidated financial statements present fairly, in all material respects, the financial position of the Company at December 31, 2025 and 2024, and the results of its operations and its cash flows for the years then ended, in conformity with accounting principles generally accepted in the United States of America.    
Auditor Name Weinberg & Company, P.A    
Auditor Location Los Angeles, California