Annual report pursuant to Section 13 and 15(d)


Cover - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Mar. 21, 2023
Jun. 30, 2022
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2022    
Document Fiscal Period Focus FY    
Document Fiscal Year Focus 2022    
Current Fiscal Year End Date --12-31    
Entity File Number 001-38418    
Entity Registrant Name Cocrystal Pharma, Inc.    
Entity Central Index Key 0001412486    
Entity Tax Identification Number 35-2528215    
Entity Incorporation, State or Country Code DE    
Entity Address, Address Line One 19805 North Creek Parkway    
Entity Address, City or Town Bothell    
Entity Address, State or Province WA    
Entity Address, Postal Zip Code 98011    
City Area Code (305)    
Local Phone Number 425-1780    
Title of 12(b) Security Common Stock, par value    
Trading Symbol COCP    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity Public Float     $ 38.0
Entity Common Stock, Shares Outstanding   8,143,332  
Documents Incorporated by Reference Portions of the registrant’s definitive proxy statement for its 2022 Annual Meeting of Stockholders are incorporated by reference in Items 10, 11, 12, 13, and 14 of Part III of this Annual Report on Form 10-K    
ICFR Auditor Attestation Flag true    
Auditor Firm ID 572    
Auditor Name Weinberg & Company    
Auditor Location Los Angeles, California