Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies (Details Narrative)

Commitments and Contingencies (Details Narrative) - USD ($) $ in Thousands		1 Months Ended		3 Months Ended		12 Months Ended
	Sep. 01, 2018	Nov. 30, 2018	Sep. 30, 2018	Mar. 31, 2019	Mar. 31, 2018	Dec. 31, 2018
Operating expenses				$ 2,201	$ 2,067
Rent expense				0	11
Right of use asset obtained in exchange for operating lease liability				833
Amortization expense recognized for operating leases				31
Operating lease expense				43
Short-term operating lease expense				12
Accumulated depreciation						$ 6
Depreciation expense				23	15
Right-of-use assets exchanged for finance lease liabilities						$ 347
Finance lease liabilities current and long-term				279
Finance lease interest expense				16
Operating lease payment				27
Payments on finance lease liabilities				(52)
Interest expense, net					32
Dr. Phillip Frost [Member]
Lease term	3 years		3 years
Lease termination, description	The lease term is three years with an optional three year extension.
Rent expense	$ 58		$ 58
Operating Leases [Member]
Operating leases weighted average discount rate				8.00%
Weighted average remaining operating lease term				4 years 6 months
Common Area Maintenance [Member]
Operating variable lease expense				$ 16	17
Operating lease expense				43	$ 42
Finance Leases [Member]
Weighted average finance lease discount rate		8.00%
Weighted average remaining finance lease term		1 year 4 months 24 days
Right-of-use lab equipment				347
Accumulated depreciation				23
Depreciation expense				17
Operating lease payment				$ 52
Finance Leases [Member] \| Lab Equipment [Member]
Lease term				5 years
February 2019 through January 2024 [Member]
Lease term				60 months
February 2019 [Member]
Lease term				5 years
Lease termination, description				The minimum lease payments above include the amounts that would be paid if the Company maintains its Bothell lease for the five-year term, starting February 2019. The Company has the right to terminate this lease after three years on January 31, 2022, by giving prior notice at least nine months before the early termination date and by paying a termination fee equal to the sum of unamortized leasing commissions and reimbursement for tenant improvements provided by the landlord amortized at 8.0% over the extended term.
Unamortized leasing percentage				8.00%
May 27, 2020 [Member] \| Lease Agreement One [Member]
Lease term		18 months
Capital lease payment		$ 18
November 21, 2021 [Member] \| Lease Agreement Two [Member]
Lease term		36 months
Capital lease payment		$ 1
Miami, Florida [Member]
Lease expire				Aug. 31, 2021
Bothell, Washington [Member]
Lease expire				Jan. 31, 2024