Annual report pursuant to Section 13 and 15(d)

Warrants - Summary of Warrant Activity (Details)

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Warrants - Summary of Warrant Activity (Details) - shares
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Warrant [Member]      
Number of warrants outstanding, beginning 8,380,000 26,769,000
Warrants acquired in merger with Biozone     21,169,000
Number of warrants issued     5,500,000
Number of warrants exercised (111,000) (18,289,000)  
Number of warrants expired (1,994,000)    
Number of warrants outstanding, ending 62,750,000 8,380,000 26,769,000
January 2012 Warrants [Member] | Equity [Member]      
Number of warrants outstanding, beginning 650,000 650,000
Warrants acquired in merger with Biozone     650,000
Number of warrants issued    
Number of warrants exercised    
Number of warrants expired (650,000)    
Number of warrants outstanding, ending 650,000 650,000
Warrant expiration date Jan. 11, 2016    
March 2013 Warrants [Member] | Equity [Member]      
Number of warrants outstanding, beginning 455,000 455,000
Warrants acquired in merger with Biozone     455,000
Number of warrants issued    
Number of warrants exercised    
Number of warrants expired 455,000    
Number of warrants outstanding, ending 455,000 455,000
Warrant expiration date Mar. 01, 2016    
April 2013 Warrants [Member] | Equity [Member]      
Number of warrants outstanding, beginning 1,500,000 1,864,000
Warrants acquired in merger with Biozone     1,864,000
Number of warrants issued    
Number of warrants exercised   (364,000)  
Number of warrants expired    
Number of warrants outstanding, ending 1,500,000 1,500,000 1,864,000
Warrant expiration date Apr. 25, 2018    
February 2012 Warrants [Member] | Liabilities [Member]      
Number of warrants outstanding, beginning 1,000,000 1,000,000
Warrants acquired in merger with Biozone     1,000,000
Number of warrants issued    
Number of warrants exercised (111,000)  
Number of warrants expired (889,000)    
Number of warrants outstanding, ending 1,000,000 1,000,000
Warrant expiration date Feb. 28, 2016    
August 2013 Warrants [Member] | Liabilities [Member]      
Number of warrants outstanding, beginning 10,000,000
Warrants acquired in merger with Biozone     10,000,000
Number of warrants issued    
Number of warrants exercised (10,000,000)  
Number of warrants outstanding, ending 10,000,000
Warrant expiration date Aug. 26, 2023    
October 2013 Warrants [Member] | Liabilities [Member]      
Number of warrants outstanding, beginning 200,000
Warrants acquired in merger with Biozone     200,000
Number of warrants issued    
Number of warrants exercised (200,000)  
Number of warrants outstanding, ending 200,000
Warrant expiration date Oct. 18, 2018    
October 2013 Warrants Series A [Member] | Liabilities [Member]      
Number of warrants outstanding, beginning 775,000 7,100,000
Warrants acquired in merger with Biozone     7,000,000
Number of warrants issued    
Number of warrants exercised (6,225,000)  
Number of warrants outstanding, ending 775,000 775,000 7,100,000
Warrant expiration date Oct. 24, 2023    
January 2015 Warrants [Member] | Liabilities [Member]      
Number of warrants outstanding, beginning 4,000,000 5,500,000
Warrants acquired in merger with Biozone    
Number of warrants issued     5,500,000
Number of warrants exercised (1,500,000)  
Number of warrants outstanding, ending 4,000,000 4,000,000 5,500,000
Warrant expiration date Jan. 16, 2024